Easy Cake Mix Blueberry Muffins
Easy Cake Mix Blueberry Muffins made with lemon cake mix, sour cream, and fresh blueberries. Bakery-style muffins ready in 28 minutes with no measuring flour or sugar.

SAVE THIS RECIPE FOR LATER!
Making muffins from cake mix is the easiest shortcut in baking! The lemon cake mix gives them a citrus flavor that works perfectly with blueberries, while the sour cream and butter keep them rich and moist. You get balanced flavor, not just a sugar bomb.
One reader added lemon zest on top of the lemon cake mix and said they were the best lemon blueberry muffins she’d ever made, so it’s worth trying!
The one thing that matters most: fold the blueberries in gently by hand at the end with a spatula, not a mixer. Overmixing bursts the berries and turns the whole batter purple.
What you’ll love about these blueberry muffins with cake mix:
Ingredients
Lemon cake mix (1 box, 15.25 oz): The base of the recipe. Duncan Hines and Betty Crocker both work. Yellow cake mix, white cake mix, or French vanilla all substitute well, lemon just complements blueberries best. One reader used sugar-free cake mix with lemon zest and said it worked perfectly.
Sour cream (1 cup, full fat): Keeps the muffins moist and tender. Full fat plain Greek yogurt is a direct substitute and works just as well.
Butter (¼ cup, melted): Salted or unsalted both work. Make sure it’s melted but not scorching hot or it will cook the eggs when you mix.
Eggs (2 large): Let them come to room temperature for better mixing.
Fresh blueberries (2 cups): Fresh gives the best flavor and texture. If using frozen don’t thaw them first, add them straight from the freezer or they’ll bleed into the batter and turn everything purple.
Sparkling sugar (1½ tsp, optional): Adds crunch and a bakery-style look on top. Regular granulated sugar works too or skip it entirely.

How Do You Make Muffins from Cake Mix?
Step 1: Preheat oven to 375°F. Line a muffin pan with paper liners or spray with baking spray.
Step 2: In a medium bowl whisk together the sour cream, melted butter, and eggs until well combined.
Step 3: Add the lemon cake mix and whisk until no dry spots remain.
Step 4: Gently fold in the blueberries with a spatula until evenly distributed. Don’t overmix or the berries will burst.
Step 5: Scoop the batter into the prepared muffin pan, filling each about ¾ full. Sprinkle sparkling sugar on top if using.
Step 6: Bake 23 to 25 minutes until golden brown on top and a toothpick inserted in the center comes out with just a few moist crumbs.
Step 7: Cool slightly before serving.







PRO TIP: Don’t overmix once you add the blueberries or they’ll burst and turn your batter purple. Fold gently until just combined, a few streaks of batter are fine.

How Long Do Blueberry Muffins Keep?
Storage: Store in an airtight container at room temperature for up to 3 days or in the refrigerator for up to 5 days.
Reheating: Great at room temperature. Warm in the microwave for 10 to 15 seconds for a fresh-baked taste.
Freezing: Freeze in a freezer-safe bag for up to 3 months. Thaw at room temperature or warm in the microwave.

What Can I Add to Blueberry Muffins?
A lemon glaze drizzled over cooled muffins adds extra sweetness and citrus flavor. Just mix powdered sugar with lemon juice until pourable. One reader added a teaspoon of lemon extract to the batter and topped with lemon glaze in a loaf pan and said it was fantastic!
A streusel topping made with flour, butter, and brown sugar pressed on before baking adds bakery-style crunch. Chopped pecans or walnuts folded in with the blueberries add texture. Raspberries, blackberries, or a mix of berries can replace some or all of the blueberries.
Sour cream can be swapped for full fat plain Greek yogurt with no change in texture. Any cake mix flavor works in place of lemon, yellow, white, and French vanilla are all good substitutes. Vegetable oil or melted coconut oil can replace the butter at a 1 to 1 ratio.
Questions about these easy cake mix muffins:
Can you make muffins with cake mix?
Yes. Cake mix makes a great muffin base! It already has flour, sugar, and leavening measured in. You just add eggs, sour cream, and butter for the right texture.
Why are my muffins dry?
Almost always overbaked. Start checking at 20 minutes. They’re done when a toothpick has just a few moist crumbs — not when it comes out completely clean.
Can I use frozen blueberries?
Yes. Don’t thaw them first. Add them to the batter frozen to prevent them from bleeding purple throughout the muffins.
Can I use yellow cake mix instead of lemon?
Yes. Yellow, white, or French vanilla all work. Lemon just adds a citrus flavor that complements blueberries well.
Can I make these in a large muffin tin?
Yes. Bake at the same temperature but increase the time to about 28 to 30 minutes and check with a toothpick.
Can I make these ahead?
Yes. Bake and store at room temperature for up to 3 days or freeze for up to 3 months.

What Goes Well With Blueberry Muffins from cake mix?
Serve with morning coffee or tea. They work for breakfast with scrambled eggs and fruit, or as a snack on their own. Also good warm with butter or a drizzle of honey.
Looking for more blueberry recipes? Try our Lemon Blueberry Cookies or Buttermilk Blueberry Muffins.

Easy Cake Mix Blueberry Muffins
Equipment
Ingredients
- 1 cup Sour Cream
- 1/4 cup Unsalted Butter melted
- 2 large Eggs
- 1 (15.25 ounce) Lemon Cake Mix
- 2 cups fresh Blueberries
- 1 1/2 teaspoons Sparking Sugar optional
Instructions
- Preheat the oven to 375°F and line a muffin paper with paper liners or use baking spray. Set aside.
- In a medium bowl, whisk together the sour cream, butter and eggs. Add the lemon cake mix and whisk until there are no dry spots of cake mix left.1 cup Sour Cream,1/4 cup Unsalted Butter,2 large Eggs,1 (15.25 ounce) Lemon Cake Mix.
- Fold in the blueberries with a spatula, then scoop the batter into the prepared muffin tin. Sprinkle approximately 1/8 teaspoon of sparking sugar on top of each muffin.2 cups fresh Blueberries,1 1/2 teaspoons Sparking Sugar.
- Bake the muffins for 23-25 minutes, or until the muffin are golden brown on top and a cake tester inserted in the center comes out with a few moist crumbs attached.
Notes
Nutrition
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I love that these are made from a lemon cake mix. The sugar on top adds a nice crunch. These will be delicious on Saturday mornings.
These blueberry muffins sound delicious, i love a blueberry muffin that includes sour cream and coarse sugar on top.
This recipe sounds so amazing! I love blueberry muffins love the idea to add a streusel topping.
These look amazing. Going to need to bake these this weekend.
I hope you enjoy them!
Hi, I just made these! Enjoyed 2 with coffee! I even ate them when they were pretty warm, so shouldn’t have been so impatient! Let them rest a 10 minutes so not eating hot blueberries! Very good muffins. I used two different cupcake papers. The tulip papers a little hard to work with the muffin dough, so I’ll use regular liners next time that don’t stick up and get in the way when scooping.
So glad to hear you enjoyed them too!
What is the time difference if making these in large muffin tins
Sam, I haven’t tried it in a large muffin pan, but I would guess to bake it 25-28 minutes.
Easy to make with great taste and texture – thanks for a wonderful recipe
You’re very welcome!!
Absolutely Perfect! I just made these muffins using Sugar Free Cake Mix as I’m diabetic. I used yellow cake mix with lemon zest. I am so pleased. I followed recipe exactly- except for the Sugar Free Cake Mix. I did lightly spray the muffin liners. Next time I might add more blueberries. Thank you so much.
Yay! So happy to hear, thank you for commenting!
These were delicious and easy. I had a box of lemon cake mix to use up and decided I wanted muffins.
I added the zest of one lemon. These were the best lemon-blueberry muffins I have ever had. My husband and friends enjoyed them too!
Hi Debbie! Thank you leaving a comment, I’m so happy to hear this! Your additions sound great!
Hey, I wondering if I can use this same recipe for a layer cake in two pans? I made it as muffins and they were so good!
Hi Val! I haven’t tried it, but I don’t see why you couldn’t adapt it into a layer cake! You’ll need to adjust the baking temperature to 350°F for even baking, and I recommend dividing the batter into two 8-inch round cake pans. Bake the cakes for about 28–32 minutes, or until a toothpick inserted in the center comes out clean or with a few moist crumbs. Let me know if you try it!!
I used a loaf pan and adjusted the time a little longer. I added a teaspoon of lemon extract to enhance the lemon flavor. I topped it off with a lemon glaze too. So delicious. My husband loves it. Great recipe! Cake mix recipes are so easy! Thank you!
These are over the top AMAZING!!!
Thank you for sharing !!
Back making another batch! These muffins are delicious and so easy. Everyone wants more.
Hi Lorraine! I’m so happy to hear! Thanks for you comment!